The MSM System 400 allows users with little to no experience to successfully dissect tetrads and cells in a user-defined grid. In addition, it allows users to do mother/daughter separation (ageing studies) and automatically count discards for each position. Screening and imaging interesting cells at user-defined positions can also be made at the click of a button.
The SporePlay+ is the fastest manual dissection microscope in the world! An upright optical microscope built from the ground up specifically for single cell manipulation, with an extra-long working distance objective, a stage with click-stops in a grid and a micromanipulator that combines X, Y and Z control into a single joystick.
Tetrad dissection is a vital tool for yeast geneticists. It is a method by which sporulating yeast cells are teased apart, and the individual cells isolated. Specially designed micromanipulation tools are used to carefully separate the cells of interest, which are then transferred to a new growth medium for further study.
Single cell screening often involves using a microscope to view the morphology or growth patterns of individual cells when certain nutrients are removed or chemicals/drugs introduced. It is an essential tool to determine how microorganisms function.
Replicative lifespan (RLS) analysis is a vital tool for yeast geneticists interested in aging studies. The replicative lifespan of a yeast cell refers to the number of daughter cells one mother cell can produce before becoming senescent. In order to do this a virgin mother cell is identified and selected. The number of daughter cells produced are then counted until the mother cell becomes exhausted.