Hirotada Mori and Barry L. Wanner

Adv Exp Med Biol. 2015;883:155-68. doi: 10.1007/978-3-319-23603-2_9.

E. coli has been a critically important model research organism for more than 50 years, particularly in molecular biology. In 1997, the E. coli draft genome sequence was published. Post-genomic techniques and resources were then developed that allowed E. coli to become a model organism for systems biology. Progress made since publication of the E. coli genome sequence will be summarized.