Singer Instruments have been helping people around the world achieve painless tetrad dissection for the last 35 years

Take this classical genetics technique for example, we have made it as easy and enjoyable as playing a video game!

What is it?

A computer-driven, motorised-stage-controlled workstation for manipulating yeast and fungal spores, the MSM 400 is undeniably the most powerful tetrad dissection workstation in the world. Using a large touch-screen computer and ergonomically designed joystick and manipulator, even inexperienced users can quickly and intuitively pick and place individual cells. The built-in software contains useful protocols that automate many of the repetitive aspects in dissection, ageing, and screening studies.

How does it work?

In every MSM 400, the specially developed motor-driven stage and integrated micromanipulator are controlled with each hand in a comfortable position. The micromanipulator controls the needle, while the joystick controls all the basic functionality of the MSM 400. Users can work “head-down” using the binocular eyepieces or dissect from the video image on the screen when a camera is attached.

What does it do?

The MSM 400 allows users with little to no experience to successfully dissect tetrads in a user-defined grid. In addition, it enables users to do mother/daughter separation (ageing studies) and automatically count discards for each position. Screening and imaging interesting cells at user-defined positions can be performed at the click of a button.

What can I use it for?

Ascospore dissection of Saccharomyces cerevisiae, Schizosaccharomyces pombe and other ascospore-producing species.

Ageing Protocols

Study and record the replicative lifespan of mother cells


Screen protocols for documenting and revisiting cells of interest.

msm 400 in use

Capture your colonies

Image-capture, storage and export

Interested in seeing the MSM 400 in action?

Book a MSM 400 Demo

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a Scientific Advisor today

Call us on +44 (0)1984 640226

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