What is the MSM 400?
The MSM 400 is an intelligent semi-automated tetrad dissection workstation. It makes it quick and easy to dissect, sort and catalogue meiotic progeny, at up to 20 sets of tetrads per petri.
Big brother to the SporePlay+, the comfortable ergonomic design and precision X, Y & Z axis needle control makes the MSM 400 a firm favourite in leading genomics facilities worldwide.
“The piece of tech which made tetrad dissection easy for both students and post-docs in my lab was the MSM 400 because they saw it as something fun to use, so much so that they forgot to worry about how ‘difficult’ it is picking up and pulling spores apart.”
Sir Paul Nurse
The Francis Crick Institute, UK
Precision control
Vibration-free X/Y axis needle control and a comfortable dial for the Z axis ensure precise movements. These can be smooth or stepped at 24 or 300 microns at a time. Calibrate for right or left-handed use.
Intuitive interface
A handheld joystick and micromanipulator combine with a motorised stage and touchscreen interface to facilitate the precise localisation of individual cells.
Maintain sterility
Inverted plate holder promotes precision cell manipulation while reducing contamination risk from breath and other airborne sources.
MSM 400 workflows
Our software engineers understand your biology! We work closely with
our scientific collaborators to make sure our user interface thinks like you do.
Tetrad dissection
Ascospore dissection of Saccharomyces cerevisiae, Schizosaccharomyces pombe and other spore-producing species.
Ageing studies
Ageing protocols to study and record yeast cell replicative lifespan (RLS). Supported by image capture, storage and export.
Single-cell screening
Rapid sorting and documentation of individual cells in an orthogonal array.
E.g. for the study of spatiotemporal dynamics and morphology in developing yeast microcolonies.
“The MSM 400 has been instrumental in increasing the throughput and controllability of our single-cell screening experiments”
Nico Appold, PhD student
Jona Kayser Research Group
Max Planck Institute
Which dissection scope is right for you?
See our range of tetrad dissection solutions.
MSM 400
Semi-automated tetrad dissection
Fast, motorised stage with positional recall and touchscreen control. Ideal for teaching labs.
SporePlay+
Manual tetrad dissection
A comfortable and compact manual tetrad dissection work buddy, built for purpose.
Get in touch
Book a 30-minute slot to discuss your workflow with one of our product experts, or ask us anything.