PIXL in advancing research for the treatment of Clostridium difficile infection

Summary Clostridium difficile is a hospital infection that disproportionately affects immunosuppressed patients, including those undergoing chemotherapy and the elderly, and can in some cases be fatal. Research shows FMT treatment is often the best option for those suffering from recurrent infection. Before FMT treatment can be administered, donors must be carefully screened to ensure best […]

How can automated colony picking help overcome challenges in the development of precision probiotics?

Summary With wide-ranging therapeutic applications, probiotic research has the potential to significantly impact how we develop medications. Nevertheless, probiotic microorganisms can be difficult to work with as they are anaerobic, have strict contamination protocols, and can form tenacious colonies. Automated colony picking helps to overcome these challenges by reducing contamination risks, facilitating environmental maintenance and […]

High-throughput screening of Saccharomyces and non-saccharomyces yeast strains in beer and cider industrially relevant media

Jose E. Aguiar-Cervera1,2 and Oliver Severn21 The University of Manchester, Oxford Rd, Manchester M13 9PL2 Singer Instruments, Roadwater, Watchet TA23 0REAuthor: Prof. Daniela Delneri, FRSB, Chair in Evolutionary Genomics, Manchester Institute of BiotechnologyFunding: H2020 Marie Skłodowska‐CurieActions,Grant/Award Number: H2020‐MSCA‐ITN‐2017(764364)’  Aim To determine whether PhenoBooth+ can be used to assess the growth performance of conventional and non-conventional yeast strains. […]

Yeast Screening

What is Yeast Genetics?

The advantage of using Saccharomyces cerevisiae in Yeast Genetics Introduction Saccharomyces cerevisiae has been the model organism for most of the molecular genetics research in the past two decades for a number of reasons (1): Genetic Markers for Saccharomyces cerevisiae The nutritional requirements for yeast growth have been clearly defined over the years, and the […]