Accelerate your susceptibility testing with ROTOR+
High-throughput Minimum Inhibitory Concentration (MIC) screening, made easy.
ROTOR+ is a precision benchtop robot for easy, ultra-fast manipulation of high-density microbial arrays.
Miniaturise your MICs by arraying to 96, 384, 1536, 6144 colonies/plate (or even higher!) to save on consumables and time.
Over 99% transfer efficiency across a range of model (S. cerevisiae, E. coli,
C. reinhardtii) and non-model organisms – even filamentous fungi.
2,000+ happy microbiologists and counting.
High-throughput MIC screening using ROTOR+
Professor Blair and her lab at the University of Birmingham using ROTOR+ to run a large-scale MIC assay on a range of clinical, environmental and genetically-engineered strains simultaneously.
Using ROTOR+ to pin from broth to agar, the Blair Lab were able to use an agar-based method to determine the (MIC) of their isolates.
The lab group using ROTOR+ to plate 100s of strains on a single PlusPlateTM
“We worked out that if we screened 96 strains against the antibiotics we wanted to test, it would take 72 multiwell plates to do the assay in broth. With all the tips needed, this is an insane amount of plastic. Being able to fit 100s of strains on an agar SBS plate (with technical replicates) means we only needed 1 PlusPlateTM per antibiotic concentration when we do the Agar MIC with ROTOR+.”
Professor Jessica Blair
The Blair Lab, University of Birmingham
(1) Bean GJ, Jaeger PA, Bahr S, Ideker T. Development of ultra-high-density screening tools for microbial “omics”. PLoS One. 2014 Jan 21;9(1):e85177. https://doi.10.1371/journal.pone.0085177
OM(G)-ics!
Cloning resistant mutants en mass?
Trey Ideker and colleagues at the University of San Diego successfully used ROTOR to plate a mind blowing 24576 individual colonies on a single plate.1
What’s more they achieved equal or better precision than alternative methods, revolutionising high-throughput screening.
“For scalability and high throughput the ROTOR+ has allowed us to phenotype
thousands of strains, which otherwise would not have been possible.”
Professor Joseph Schacherer
Strasbourg University, co-founder of the 1002 Yeast Genomes Project.
Want to accelerate your AST testing with ROTOR+?
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