Resources

Finding the yeast cell cycle CDK

How we used yeast to find the cornerstone cell cycle CDK regulator Cyclin-dependent kinases (CDKs) are multifunctional enzymes found in our cells which phosphorylate (add phosphate chemical groups) to target proteins [1,2]. Once phosphorylated a target protein’s location, function and stability can be altered which in turn affects the behaviour of the cell. All eukaryotes […]

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How to Grow Yeast

Your step-by-step guide 15/03/2018 Introduction Here we will show you some quick easy ways to grow yeast in the lab. Yeast is one of the simplest eukaryotic organisms with which we share a common ancestor (albeit over a billion years ago) meaning yeast cells share many basic properties with our own cells. They also come […]

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Citations

Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast

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Dependency of Heterochromatin Domains on Replication Factors

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RNA metabolism is the primary target of formamide in vivo

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Rho1-GEFs Rgf1 and Rgf2 are involved in formation of cell wall and septum, while Rgf3 is involved in cytokinesis in fission yeast

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Hot spots of recombination in fission yeast: inactivation of the M26 hot spot by deletion of the ade6 promoter and the novel hotspot ura4-aim

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Molecular analysis of the essential gene for adenylate kinase from the fission yeast Schizosaccharomyces pombe

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Role of the two type II myosins, Myo2 and Myp2, in cytokinetic actomyosin ring formation and function in fission yeast

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Cytokinetic actomyosin ring formation and septation in fission yeast are dependent on the full recruitment of the polo-like kinase Plo1 to the spindle pole body and a functional spindle assembly checkpoint

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Fission yeast Pds5 is required for accurate chromosome segregation and for survival after DNA damage or metaphase arrest

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Involvement of Schizosaccharomyces pombe Srs2 in cellular responses to DNA damage

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Cid1, a Fission Yeast Protein Required for S-M Checkpoint Control when DNA Polymerase delta or varepsilon Is Inactivated

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Spatial regulation of cytokinesis by the Kin1 and Pom1 kinases in fission yeast

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Growth arrest and chromosome instability in aneuploid yeast

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A critical role for the type V myosin, Myo52, in septum deposition and cell fission during cytokinesis in Schizosaccharomyces pombe

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Requirement of fission yeast Cid14 in polyadenylation of rRNAs

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btn1, the Schizosaccharomyces pombe homologue of the human Batten disease gene CLN3, regulates vacuole homeostasis

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Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects

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The meiotic recombination hot spot ura4A in Schizosaccharomyces pombe

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Mcp6, a meiosis-specific coiled-coil protein of Schizosaccharomyces pombe, localizes to the spindle pole body and is required for horsetail movement and recombination

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Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast

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The Clp1p/Flp1p phosphatase ensures completion of cytokinesis in response to minor perturbation of the cell division machinery in Schizosaccharomyces pombe

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The C-terminal zinc finger of the catalytic subunit of DNA polymerase delta is responsible for direct interaction with the B-subunit

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Fission yeast cdc31p is a component of the half-bridge and controls SPB duplication

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Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinase

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MCM-GINS and MCM-MCM interactions in vivo visualised by bimolecular fluorescence complementation in fission yeast

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Mug27 is a meiosis-specific protein kinase that functions in fission yeast meiosis II and sporulation

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Break-induced loss of heterozygosity in fission yeast: dual roles for homologous recombination in promoting translocations and preventing de novo telomere addition

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Mcp4, a meiotic coiled-coil protein, plays a role in F-actin positioning during Schizosaccharomyces pombe meiosis

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The Schizosaccharomyces pombe fusion gene hal3 encodes three distinct activities

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Modification of tRNALysUUU by Elongator Is Essential for Efficient Translation of Stress mRNAs

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Abc3-Mediated Efflux of an Endogenous Digoxin-like Steroidal Glycoside by Magnaporthe oryzae Is Necessary for Host Invasion during Blast Disease. PLoS pathogens

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Genetic analysis of meiotic recombination in Schizosaccharomyces pombe

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Regulation of the nuclear poly(A)-binding protein by arginine methylation in fission yeast

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The deubiquitinating enzyme Ubp21p of fission yeast stabilizes a mutant form of protein kinase Prp4p

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Fission yeast homologs of human CENP-B have redundant functions affecting cell growth and chromosome segregation

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spp42, identified as a classical suppressor of prp4-73, which encodes a kinase involved in pre-mRNA splicing in fission yeast, is a homologue of the splicing factor Prp8p

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Srp2, an SR protein family member of fission yeast: in vivo characterization of its modular domains

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A centromere DNA-binding protein from fission yeast affects chromosome segregation and has homology to human CENP-B

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Nuclear export competence of pre-40S subunits in fission yeast requires the ribosomal protein Rps2

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High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe

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Tls1 regulates splicing of shelterin components to control telomeric heterochromatin assembly and telomere length

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Identification of Genes Affecting the Toxicity of Anti-Cancer Drug Bortezomib by Genome-Wide Screening in S. pombe

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Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

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Elimination of shelterin components bypasses RNAi for pericentric heterochromatin assembly

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Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases

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